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Anastrozole has been tested for reducing estrogens, including estradiol, in men.  Excess estradiol in men can cause benign prostatic hyperplasia , gynecomastia , and symptoms of hypogonadism . It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer.  Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen-- gynecomastia , emotional lability and water retention.  Study data suggest dosages of mg to 1 mg a day reduce serum estradiol by approximately 50% in men, which differs in postmenopausal women.