Human Growth Hormone is an injectable hormone that can be administered subcutaneously or intramuscularly. When injected subcutaneously, HGH carries a bioavailability of approximately seventy-five percent. When injected intramuscularly, HGH carries a bioavailability of approximately sixty-three percent. The mode of administration will also affect the half-life of the Somatropin hormone. When injected subcutaneously, it will carry a half-life of approximately hours. When injected intramuscularly, it will carry a half-life of approximately hours. While this is a rather short half-life regardless of the mode of administration, keep in mind the total effects far outlast these numbers due to the pronounced and significant increases in IGF-1 production that stretch far past the twenty-four hour mark.
Supplementing with L-glutamine is known for enhancing exercise performance, maintaining acid-base balance and increasing the storage of glycogen in muscle. In an Iranian study, 30 healthy non-athlete males were randomly divided into placebo and glutamine supplementation groups and put through an eight-week resistance training program. Both groups performed the same weight training program three days a week for eight weeks. Both groups increased in performance, but the glutamine groups showed greater increases in lower- and upper-body strength, explosive muscle power, blood testosterone, IGF-1, and HGH compared to the placebo group. ( 16 )