Equipoise can produce androgenic side effects such as acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. However, the overall androgenicity of this steroid is greatly reduced due to the structural nature that creates EQ in its double bond at the carbon one and two position. Such side effects of Equipoise are still possible, but they will be strongly linked to genetic predisposition, but most will find the threshold is fairly high.
When combating the possible androgenic side effects of Equipoise, it’s important to note they are brought on by the steroid being metabolized by the 5-alpha reductase enzyme. This metabolism will reduce Boldenone to an extremely potent androgen in dihydroboldenone, far more potent than dihydrotestosterone (DHT); however, the total dihydroboldenone activity has proven to be extremely low in human beings. You will further find the androgenic nature of Boldenone will not be significantly affected by 5-alpha reductase inhibitors like Finasteride that are often used to combat the reduction to DHT.
Due to the androgenic nature of Equipoise, women may potentially experience virilization symptoms. Virilization symptoms may include body hair growth, a deepening of the vocal chords and clitoral enlargement. However, the low androgenicity will make this steroid possible to use for some women without such symptoms. At the same time, the extremely slow acting nature of the compound can make it difficult to control regarding blood levels, and alternative steroids may be preferred. Without question, individual sensitivity will dictate a lot. If Equipoise is used and virilization symptoms begin to show, use should be discontinued immediately at their onset and they will fade away. If symptoms begin to show and are ignored, the symptoms may become irreversible.
Laws and Penalties: Concerns over growing illegal AAS abuse by teenagers, and many of the just discussed long-term effects, led Congress in 1991 to place the whole AAS class of drugs into Schedule III of the Controlled Substances Act (CSA). Under this legislation, AAS are defined as any drug or hormonal substance, chemically and pharmacologically related to T (other than estrogens, progestins, and corticosteroids) that promotes muscle growth. The possession or sale of AAS without a valid prescription is illegal. Since 1991, simple possession of illegally obtained AAS carry a maximum penalty of one year in prison and a minimum $1,000 fine if this is an individual’s first drug offense. The maximum penalty for trafficking (selling or possessing enough to be suspected of selling) is five years in prison and a fine of $250,000 if this is the individual’s first felony drug offense. If this is the second felony drug offense, the maximum period of imprisonment and the maximum fine both double. While the above listed penalties are for federal offenses, individual states have also implemented fines and penalties for illegal use of AAS. State executive offices have also recognized the seriousness of AAS abuse and other drugs of abuse in schools. For example, the State of Virginia enacted a law that will allow student drug testing as a legitimate school drug prevention program (48, 49).