what were your son's symptoms, how did you notice, and what did you think that made you realize he had hypothyroidism.? I know they say you gain weight initially when put on steroids, but I was told it should stabilize at a certain point and they should not gain much after that. my son is still gaining. he has gained a total of 35 lbs in less than 2 1/2 years. for example from nov 2010 to may 2011 he gained another 12 lbs. I have now been told he is considered obese. I think if he could have not gained so much, or could lose what he has gained he would be able to move around alot better. his symptoms are as follows and I thought that with some of them they should not be from dmd: sluggish, tired, very slow when walking, thick skin, skin rash, coarse hair, weight gain, constipation at times, aches and pains in his joints, and just cannot lose any weight with exercise and his daily intake for calories is between 1200-1500. are any of these what you son had. his ck-mb level is also elevated, which is supposed to mean myocardial infarction but can also mean signs of hypothyroidism. any info you might have I would appreciate it. thanks so much
Negative result does not rule out hypothyroidism, and no assessment of thyroid function Measurement confirms the presence of lymphocytic thyroiditis – but this is not the pathology present in all dogs (some studies suggest 50% of cases), and levels decline with decreased thyroid tissue so is only helpful in early cases. Some breeders are using this as a screening test in young dogs of breeds known to be predisposed to hypothyroidism. In such cases TGAA can be used as a marker of thyroid disease in dogs which are at present clinically healthy.
T3 is derived from T4 by enzymatic conversion in the blood and peripheral tissues. T3 is the more active form of thyroid hormone, and binds to nuclear thyroid hormone receptors in different cells and tissues. In contrast to T4 which has a long half-life of several days, T3 has a short half life (hours), and disappears more rapidly from our blood after a single dose. Furthermore, T3 is much more potent, and if taken in excessive dosages, T3 may rapidly cause problems such as fast heart beats and palpitations, increased sweating or anxiety, increased blood pressure, and in some patients, even chest pain (angina). T3 is often used for a brief period of time following thyroid surgery for thyroid cancer, following which the T3 is discontinued prior to administration of radioactive iodine. There are some reports suggesting that patients with hypothyroidism treated with T3 alone, or T3 in combination with T4 feel better and may experience less depression than patients treated with thyroxine alone. Only a few small studies have been carried out to examine this issue, and more information and larger studies are clearly warranted to examine the risks and benefits of T3 administration, as reviewed in Optimal Thyroid Hormone Replacement.